Will Big Logistics Move Into Cannabis – Or Stay on the Sidelines?

As the U.S. cannabis market surges—projected to top $57 billion this year, with a forecast of nearly $800 billion by 2032—its supply chain has become a critical pain point. State-legal operators scramble to manage complex intra‑state logistics. But when it comes to nationwide players like UPS, FedEx, DHL, conventional wisdom is that inevitable entry may not play out as expected.

Federal Law: A Binding Barrier

The central deterrent remains federal prohibition. Marijuana remains classified as a Schedule I substance under the Controlled Substances Act, prohibiting interstate transport. This ban isn’t symbolic—couriers actively detect and confiscate shipments. Confidential sources report that UPS, FedEx, and DHL cooperate with law enforcement and routinely intercept cannabis shipments. UPS’s internal policy explicitly bars marijuana shipments—even in states where cannabis is legal—and reserves the right to destroy packages showing signs of cannabis.

Corporate Risk & Compliance Burden

Beyond legal prohibition, major logistics firms must weigh reputational, financial, and compliance risks. Transporting high‑value cannabis requires armored transport, GPS tracking, secure storage, video monitoring, and trained personnel. A 2021 Food Logistics report highlighted that even 3PLs entering cannabis often relied on partners like Onfleet, Nabis, or Distru for security features. To build this infrastructure from scratch, firms would face steep upfront costs and mounting regulatory exposure.

Limited Scope: Hemp & CBD Only

Major carriers have cautiously expanded into hemp-derived CBD logistics under the 2018 Farm Bill, provided THC remains under 0.3%. UPS and FedEx allow hemp‑CBD shipments, but they sharply restrict origin points, drop-off locations, and partner criteria. DHL similarly bans THC‑rich products. This indicates a strategic pivot toward federally legal substance logistics, without infringing marijuana’s federal prohibitions.

An Emergent Cannabis‑Only Logistics Ecosystem

As mainstream carriers stay out, an ecosystem of specialized cannabis logistics providers has flourished. Companies like Nabis, Greenlane, Stem Holdings, Green Parcel Service, and Talaria operate state‑licensed transport services, complete with compliance, secure fleets, and real‑time inventory systems. Distru reports that U.S. cannabis distribution will exceed $45 billion in 2025 alone, spurred by the need for temperature control, tracking, and regulatory navigation.

Will Big Logistics Ever Engage?

Unlikely unless Congress reclassifies cannabis at the federal level. While cannabis advocates push for de‑scheduling or rescheduling, no legislative breakthroughs are imminent. Until then, national carriers are highly unlikely to enter the THC logistics space—legal uncertainty, internal risk tolerance, and costly compliance frameworks leave them with “better‑to‑sit‑this‑one‑out” incentives.

In Summary

The U.S. cannabis supply chain continues expanding rapidly—but national logistics giants remain tied to federal and regulatory constraints. Instead, cannabis‑centric logistics firms have carved out niche dominance, evolving with state‑by‑state legal frameworks and building trust inside the green economy. Unless a sweeping federal legalization effort passes, major carriers are expected to stay on the sidelines, even as smaller specialists deepen their grip on this growing market.